Selected Publications

Zwang TJ, Sastre ED, Wolf N, Ruiz-Uribe N, Woost B, Hoglund Z, Fan Z, Bailey J, Nfor L, Buée L, Nilsson KPR, Hyman BT, Bennett RE. Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology. Cell Rep. 2024 Aug 2;43(8):114574. doi: 10.1016/j.celrep.2024.114574. Epub ahead of print. PMID: 39096489.

Hoglund Z, Ruiz-Uribe N, Del Sastre E, Woost B, Bader E, Bailey J, Hyman BT, Zwang T, Bennett RE. Brain vasculature accumulates tau and is spatially related to tau tangle pathology in Alzheimer's disease. Acta Neuropathol. 2024 Jun 17;147(1):101. doi: 10.1007/s00401-024-02751-9. PMID: 38884806; PMCID: PMC11182845.

Bryant A, Li Z, Jayakumar R, Serrano-Pozo A, Woost B, Hu M, Woodbury ME, Wachter A, Lin G, Kwon T, Talanian RV, Biber K, Karran EH, Hyman BT, Das S, Bennett R. Endothelial Cells are Heterogeneous in Different Brain Regions and are Dramatically Altered in Alzheimer's Disease. J Neurosci. 2023 May 17:JN-RM-0237-23. doi: 10.1523/JNEUROSCI.0237-23.2023. Epub ahead of print. PMID: 37208174.

Zwang TJ, Woost B, Bailey J, Hoglund Z, Richardson DS, Bennett RE, Hyman BT. Spatial characterization of tangle-bearing neurons and ghost tangles in the human inferior temporal gyrus with three-dimensional imaging. Brain Commun. 2023;5(3):fcad130. doi: 10.1093/braincomms/fcad130. eCollection 2023. PubMed PMID: 37324243; PubMed Central PMCID: PMC10263274

Zwang TJ, Bennett RE, Lysandrou M, Woost B, Zhang A, Lieber CM, Richardson DS, Hyman BT. Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue. Elife. 2023 Jan 19;12. doi: 10.7554/eLife.84112. PubMed PMID: 36656755; PubMed Central PMCID: PMC9889093.

Bryant AG, Manhard MK, Salat DH, Rosen BR, Hyman BT, Johnson KA, Huang S, Bennett RE, Yen YF. Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD. Curr Alzheimer Res. 2021;18(9):711-720. doi: 10.2174/1567205018666211126113904. PubMed PMID: 34825871; PubMed Central PMCID: PMC8822690.

Bryant AG, Hu M, Carlyle BC, Arnold SE, Frosch MP, Das S, Hyman BT, Bennett RE. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Front Neurol. 2020;11:575953. doi: 10.3389/fneur.2020.575953. eCollection 2020. PubMed PMID: 33041998; PubMed Central PMCID: PMC7525127.

Bennett RE, Hu M, Fernandes A, Perez-Rando M, Robbins A, Kamath T, Dujardin S, Hyman BT. Tau reduction in aged mice does not impact Microangiopathy. Acta Neuropathol Commun. 2020 Aug 18;8(1):137. doi: 10.1186/s40478-020-01014-4. PubMed PMID: 32811565; PubMed Central PMCID: PMC7436970.

Wegmann S, Bennett RE, Delorme L, Robbins AB, Hu M, McKenzie D, Kirk MJ, Schiantarelli J, Tunio N, Amaral AC, Fan Z, Nicholls S, Hudry E, Hyman BT. Experimental evidence for the age dependence of tau protein spread in the brain. Sci Adv. 2019 Jun;5(6):eaaw6404. doi: 10.1126/sciadv.aaw6404. eCollection 2019 Jun. PubMed PMID: 31249873; PubMed Central PMCID: PMC6594764.

Bennett RE, Bryant A, Hu M, Robbins AB, Hopp SC, Hyman BT. Partial reduction of microglia does not affect tau pathology in aged mice. J Neuroinflammation. 2018 Nov 9;15(1):311. doi: 10.1186/s12974-018-1348-5. PubMed PMID: 30413160; PubMed Central PMCID: PMC6230271.

Bennett RE, Robbins AB, Hu M, Cao X, Betensky RA, Clark T, Das S, Hyman BT. Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1289-E1298. doi: 10.1073/pnas.1710329115. Epub 2018 Jan 22. PubMed PMID: 29358399; PubMed Central PMCID: PMC5819390.

Wegmann S, Bennett RE, Amaral AS, Hyman BT. Studying tau protein propagation and pathology in the mouse brain using adeno-associated viruses. Methods Cell Biol. 2017;141:307-322. doi: 10.1016/bs.mcb.2017.06.014. Epub 2017 Jul 25. PubMed PMID: 28882310.

Bennett RE, DeVos SL, Dujardin S, Corjuc B, Gor R, Gonzalez J, Roe AD, Frosch MP, Pitstick R, Carlson GA, Hyman BT. Enhanced Tau Aggregation in the Presence of Amyloid β. Am J Pathol. 2017 Jul;187(7):1601-1612. doi: 10.1016/j.ajpath.2017.03.011. Epub 2017 May 10. PubMed PMID: 28500862; PubMed Central PMCID: PMC5500829.

Explore data from Bryant J Neurosci 2023